ASSESSMENT OF SENSITISING PROPERTIES IN VITRO : KERATINOSENS*

OECD 442D

 KeratinoSens™ is the first biological assay for skin sensitisation testing validated by EURL ECVAM (The European Union Reference Laboratory for Alternatives to Animal Testing)

  • The method is based upon an engineered skin cell line that emits light if contacted by an allergen ;
  • KeratinoSens™ is based upon a genetically engineered cell line (HaCaT) which contains the luciferase firefly gene regulated in such a way that light is emitted if the cells are contacted by an allergen. The intensity of the light signal provides a means of measurement of the risk of skin sensitisation.

*Done with partner

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€ : < 1500 € €€ : between 1500 and 4000 € €€€ : between 4000 and 20000 € €€€€ : > 20000 €
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