Studies are designed according to international guidelines, including OECD, EC, OPPTS, ICH or Japanese guidelines.
Central Nervous System
Experimental Testing
| Guideline | Study |
| ICH S7A |
Neurobehavioural Observation test / Functions Observation Battery (FOB): Irwin test |
| ICH S7A |
Motor coordination : Rotarod test |
| ICH S7A |
Pro-convulstant effect |
| ICH S7A |
Effects on vigilance: exobarbital-induced sleeping time |
Gastro Intestinal System
Experimental Testing
| Guideline | Study |
| ICH S7A |
Charcoal transit time |
| ICH S7A |
Gastric emptying and secretion (solid or liquid) |
| ICH S7A |
Ulcerogenic effect |
Analgesy / Coagulation
Experimental Testing
| Guideline | Study |
| ICH S7A |
Central analgesia : Hot plate test |
| ICH S7A |
Central and peripheral analgesia : Randall and Selitto test |
| ICH S7A |
Anti inflammatory effect : Paw oedema volume |
| ICH S7A |
Bleeding time |
